Located in the heart of Oneonta, New York, at 261-267 Main St, Wise Guys Sammy's stands as a local landmark for those seeking a genuine and welcoming dining experience. Our establishment is built on the foundation of providing high-quality, hearty meals in an environment that feels like a home away from home. Whether you are a long-time resident of the community or a visitor passing through the scenic landscapes of Upstate New York, our doors are open to provide you with a memorable meal that emphasizes fresh ingredients and careful preparation.
We believe that a great restaurant is defined not just by the food on the plate, but by the atmosphere and the connection shared between the kitchen and the guest. At Wise Guys Sammy's, we take pride in our role within the local neighborhood, serving as a gathering place where friends meet, families celebrate, and individuals can enjoy a quiet moment over a well-crafted dish. Our commitment to consistency and quality ensures that every visit meets the expectations of our patrons, making us a staple of the Main Street corridor.
What Makes Us Unique
Community-Focused Atmosphere: We prioritize creating a space that reflects the spirit of Oneonta, offering a comfortable setting that is suitable for casual lunches, relaxed dinners, and everything in between.
Dedication to Quality Ingredients: Our kitchen team focuses on sourcing reliable components to ensure that every dish served maintains a high standard of flavor and freshness, reflecting our respect for traditional culinary techniques.
Central Location: Situated conveniently at 261-267 Main St, our restaurant is easily accessible for those exploring the downtown area, making it a perfect stop during a busy day or a planned evening out in the city.
Consistent Hospitality: We strive to provide attentive and friendly service to every guest, ensuring that your time spent with us is pleasant, efficient, and focused on your enjoyment of the meal.
A Commitment to Our Guests
The culinary philosophy at Wise Guys Sammy's is rooted in the idea that food should be approachable, satisfying, and prepared with integrity. We understand that our guests have many choices when it comes to dining in Oneonta, which is why we work diligently to maintain the trust and loyalty of our community. By focusing on the fundamentals of good cooking and genuine hospitality, we aim to contribute positively to the vibrant local food scene that makes our city special.
As we continue to serve the Oneonta area, our goal remains simple: to provide a reliable dining destination where quality is never compromised. We invite you to visit us on Main Street to experience the care and effort that goes into every aspect of our service. Whether you are looking for a quick bite or a place to settle in for a longer meal, we look forward to welcoming you to our table and sharing the unique character of Wise Guys Sammy's with you.
Thank you for considering us for your next dining experience. We are proud to be a part of the Oneonta community and look forward to serving you soon. Our team is always ready to provide a welcoming environment where you can relax, enjoy a great meal, and appreciate the simple pleasures of dining out in a place that truly values its customers.
Amenities and More
Accessibility
Wheelchair accessible entrance
Wheelchair accessible parking lot
Wheelchair accessible restroom
Wheelchair accessible seating
Service options
No-contact delivery
Delivery
Onsite services
Takeout
Dine-in
Highlights
Fast service
Serves local specialty
Popular for
Lunch
Dinner
Solo dining
Offerings
Alcohol
Beer
Cocktails
Coffee
Comfort food
Quick bite
Small plates
Vegetarian options
Wine
Dining options
Breakfast
Lunch
Dinner
Catering
Dessert
Seating
Table service
Amenities
Restroom
Atmosphere
Casual
Cozy
Trendy
Crowd
College students
Family-friendly
Groups
LGBTQ+ friendly
Tourists
Planning
Accepts reservations
Payments
Checks
Credit cards
Debit cards
NFC mobile payments
Credit cards
Children
Good for kids
Parking
Free street parking
Usually plenty of parking
Menus
Signature Selections
Menu
Chicken Wings
Menu
Cheese Calzones
Menu
Wise Guys Pizza
Menu
Wise Guys Vegetarian Choice
Menu
Sides
Menu
Salads
Menu
Strombolis
Menu
Drinks
Menu
Hand Crafted from the Grill
Menu
Daily Specials
Menu
Wise Guys Cluckin' Sammys
Menu
Dessert
Menu
Build Your Own Sammy
Menu
Fat Sammys
Menu
Side sauces
Menu
Breakfast Sammy
Menu
Photos
Reviews Wise Guys Sammy's
shawn gregory
30-05-2026
This place has amazing food ND even better prices. 😍. The people there are wonderful ❤️ …
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Ellen Jaiman
30-05-2026
What a wonderful place! I have been ordering and eating here since they opened in Oneonta. The bread is amazing! The sandwiches are amazing! And if you want a burger second (at a very small space) to 5 guys, order from here. The one … More
Jim
30-05-2026
The chefs salad is stellar, could have used more onions and less tomato/olive. The ciabatta sub, chicken bacon pepper jack, is perfect. More
Jamie Spear
30-05-2026
Wonderful food, love the guy that owns it! The one cashier was absolutely rude. I’m upset I had the misfortune of dealing with him, the dude with the snake tattoo. Very snarky and rude both on the phone AND in person. The girl was very nice though!! :) More
Dan Monti
30-05-2026
Nice spot, good food, a little noisy for my taste, but I have some sensory issues. Biggest issue is that people frequently intermittently are smoking by the door and, as they functionally have no AC, with the fans blowing in... More
D “Zaknafean” D
30-05-2026
Some of the greatest sandwiches you'll ever find. Tasty, filling, delicious... Don't hesitate! There's a reason their clientele is so loyal. I love the Wyatt, but everything is great. Great portions got good prices, you can't ask for more.
daniel wickey
30-05-2026
Interesting selection of burgers and sandwiches. I had the boar burger my son had the elk. We were both very happy with our selections. Very attentive staff and friendly. Looked like a great selection of beer, they had a board with … More
Ashley Allen
30-05-2026
Wise Guys is my favorite place in town. They always have great specials, and the portions are usually enough for two meals. The beer selection in the bar is always stellar too. We dined in tonight, and Nate and Jenna made it a fantastic … More
adam jeschke
30-05-2026
I think people accidentally hit 1 instead of 5 stars!!! Some people have to wear glasses next time they review! This place is amazing! Every sandwich is great! We order from work as well and never a mess up! The bread tastes great and the … More
Chrissy D
30-05-2026
Great food. Nice for a grab and go meal. Every kind of sandwich you could imagine. The ‘down state’ on a wrap, one of my favorites! Not on the menu?, they always accommodate, however you like it. They are also known for their yummy burgers … More
Jesse G
30-05-2026
Typically I try to lower my expectations when trying something for the first time, however, my expectations were high going into this spot today because everyone says it’s the best. I was not let down. They exceeded my high expectations. … More
shawn gregory
30-05-2026
This place has amazing food ND even better prices. 😍. The people there are wonderful ❤️
Order type
Dine in
Meal type
Lunch
Price per person
$20–30
Luke Stanton
30-05-2026
Service was fantastic. The lady helping me was very friendly and knowledgeable. I ordered 2 large subs. It took less than 10 mins. They were really good. Bread was fresh and all the toppings were too. The meats were tasty and the … More
Danielle Labrecque
30-05-2026
If you are anywhere in the area stop here! The food was exceptional. Fresh, homemade bread for the sandwiches like I haven’t had in years. The Italian is made with such quality. It is hands down the best I’ve had in a decade. We had … More
Blue Raspberry
30-05-2026
Wonderful food, reasonable prices, comfy space.
Wiseguys has the best fried chicken sandwich in town- see the Southern Fried. … More
nancy plaag
30-05-2026
Ordered thru door dash The Fish & fries were sooo good, especially the fish, crunchy on the outside, juicy on the inside. The California Kid Sammie was excellent Really hit the spot
Thank you Wise Guys More
Elizabeth Fitzgerald
30-05-2026
Wise Guys is always a great time—especially when Nate or Scott are working! The service is fantastic and keeps us coming back. Their personal pizzas are among my favorites in town, and I love the mozzarella sticks. Sheryl’s Veggie Melt special is SO good—I hope it becomes a regular menu item.
I appreciate the cider options since I’m not a beer drinker, and the “80 beers around the world” challenge is a fun touch. We bring our big boy Kenneth to the patio when we can—he loves the staff and meeting new people. I do wish they’d bring back the second outdoor table and maybe add more TVs and a sports package—this would be a great sports bar vibe! But overall, you won’t be disappointed!
Order type
Dine in
Meal type
Dinner
Price per person
$10–20
Food: 5
Service: 5
Atmosphere: 4
Reservation
Reservations not required
Parking space
Plenty of parking
Parking options
Free street parking
Selena Dutcher
30-05-2026
We were in Oneonta for a work day trip and stumbled upon this gem! The atmosphere was awesome and was only outshined by the DELICIOUS sandwiches! We had a difficult time deciding because every sandwich made your mouth water. It's definitely a MUST when you visit!!
Dustin Genter
30-05-2026
The food was great! Sandwiches are huge! I got a "small" and an order of fries and I could barely finish it all. Great selection of craft beer as well! Staff was super friendly also!
J Q.
30-05-2026
Came here with my college kid, self seating, quick service, tasty food (grilled mushroom burger with spicy bourbon sauce & onion rings) good prices, owner was charming...glad we stopped in! More
Amy Ortiz
30-05-2026
The sandwiches are AMAZING. We are from Chicago and my son loves sandwiches. They make their own bread and the sandwiches are HUGE and DELICIOUS. It was hard to find but it is through the doors in the picture attached. Owner is really nice.
Barbie Blacher
30-05-2026
Had to share that I had a fantastic experience during move in day. I called a month in advance because my son wanted to go there for diner. They don’t normally take reservations, but they did agree to help me out with this. The table was … More
Adaline Shultis
30-05-2026
Heard rave things so decided to try it out since there was rain off and on tonight and they had some covered outside tables. The two stars are for the homemade chips which were crunchy and delicious. The sandwich itself was nothing special … More
Giuseppe Damiano
30-05-2026
Got a hamburger and fries was very satisfied with the service, food and price. Would 100% recommend this place, waitress was very nice and helpful. The service, food and price is 5 stars. Pretty much good as it gets honestly for a nice bar and food style establishment. More
Alyssa Christman
30-05-2026
I got the vegetarian Philly cheesesteak- absolutely delicious and hit the spot perfectly! Highly recommend to those looking for plant based meat substitutes!
Order type
Take out
Meal type
Lunch
Price per person
$10–20
Food: 5
Service: 5
Atmosphere: 5
Wait time
Up to 10 min
Recommendation for vegetarians
Highly recommend
Vegetarian offerings
Clearly labeled vegetarian dishes
Ross
30-05-2026
The food is totally fine, we have no complaints there. The po'boy was tasty. The issue I run into is, as a family, it's not a very friendly place to dine in. The music is very loud, and it's much more of a bar than a restaurant.
In the future we'll probably just order and take it home. But this isn't to say they suck, their vibe just isn't it for anyone who struggles with loud noises and being in that bar atmosphere.
Order type
Dine in
Price per person
$10–20
Food: 5
Service: 4
Atmosphere: 2
Noise level
Very loud, hard to hear
Group size
Suitable for all group sizes
Dr Strang love
30-05-2026
I have been hear many times and can not recommend it enough. The food is always good. There is sometimes a weight if your a walk in. But that is the perfect time to go have a beer. Staff is always in a good mood and you can most of the time catch the owner talking to customers and asking frequent customers how things are going.
ted a izzo
30-05-2026
What a great place! Excellent food and atmosphere. Restaurant is BETTER than buffalo wild wings. They love students and if you are part of a fraternity or sorority they let you hang your letters on the wall! The staff is very friendly and truly appreciate thier patrons.
Food: 5
Service: 5
Atmosphere: 5
Max “MaxDuderino” Duderino
30-05-2026
This place is great, don't know why I haven't given a review before but I finally was able to try one of their sandwiches so it's the appropriate time for one. It was delicious and I am a sandwich man, we're talking sandwiches are one of my three food groups next to Pizza and beef. The dressing was great the bread was great the pickle slice was good and the house made chips were all so good the sauce on the sub the whole thing was just great. Beer and a big old sandwich for 20 bucks not shabby.
Price per person
$10–20
Food: 5
Service: 5
Atmosphere: 5
Noise level
Quiet, easy to talk
Group size
Suitable for all group sizes
Seating type
Indoor dining area, Bar area, Private dining room
Marc Weinmuller
30-05-2026
Wow! I'm not sure why it took me so long to get in and try this place, but the food was amazing and i will definitely return soon to try something else from the wide variety of mouth watering menu choices. The woman that took my order (Shawna, I believe) was super kind and patient, putting up with my annoying customizations. Mike was attentive and made a great suggestion (customized again) when i couldn't decide on an appropriate gluten free option for my girlfriend (she loved it too). Thank you so much for the incredible dinner and fantastic service!
Price per person
$10–20
Food: 5
Service: 5
Atmosphere: 5
Recommended dishes
Sandwich, Fries, Onion Rings
Noise level
Quiet, easy to talk
Group size
Suitable for all group sizes
Sean Doenges
30-05-2026
We are always impressed with the food, relaxed atmosphere and cold beer. The new menu has some great options and excellent sandwiches. It can be hard to find a place that has a sandwich for less than 10 bucks but they have lots of options for every budget. Also, I recommend the pesto fries they are amazing!
Order type
Dine in
Meal type
Dinner
Price per person
$10–20
Food: 5
Service: 5
Atmosphere: 5
Wait time
No wait
Reviews Wise Guys Sammy's